Virtual screening, ADME/Tox predictions and the drug repurposing concept for future use of old drugs against the COVID-19
Lorane Izabel da Silva Hage-Melim, Leonardo Bruno Federico, Nayana Keyla Seabra de Oliveira, Viviane Cristina Cardoso Francisco, Lenir Cabral Correia, Henrique Barros de Lima, Suzane Quintana Gomes, Mariana Pegrucci Barcelos, Isaque Antônio Galindo Francischini, Carlos Henrique Tomich de Paula da Silva
Topics & Concepts
In silicoVirtual screeningADMEDrug repositioningProteaseComputational biologyDrugRepurposingCoronavirusDocking (animal)Drug discoveryIndinavirViral replicationPharmacologyCoronavirus disease 2019 (COVID-19)ChemistryBiologyVirusEnzymeInfectious disease (medical specialty)BiochemistryVirologyMedicineViral loadDiseaseNursingGeneEcologyAntiretroviral therapyPathologyComputational Drug Discovery MethodsSynthesis and biological activitySARS-CoV-2 and COVID-19 Research