Synthesis, characterization and molecular docking studies of highly selective new hydrazone derivatives of anthranilic acid and their ring closure analogue Quinazolin-4(3H)-ones against lung cancer cells A549
Feyzi Sinan Tokalı, Halil Şenol, Şeyma Bulut, Ebru Hacıosmanoğlu
Topics & Concepts
ChemistryAnthranilic acidDocking (animal)A549 cellStereochemistryHydrazideEpidermal growth factor receptorIC50In vitroReceptorBiochemistryOrganic chemistryNursingMedicineQuinazolinone synthesis and applicationsSynthesis and biological activityCancer therapeutics and mechanisms