<i>Bifidobacterium bifidum</i> relieved DSS-induced colitis in mice potentially by activating the aryl hydrocarbon receptor
Qingyu Cui, Xiaoying Tian, Xi Liang, Zhe Zhang, Rui Wang, Yu Zhou, Huaxi Yi, Pi-min Gong, Kai Lin, Tongjie Liu, Lanwei Zhang
Abstract
Two Bifidobacterium bifidum strains could exert their anti-inflammatory and intestinal barrier protecting effects both in vitro and in vivo , upregulate the expression of the aryl hydrocarbon receptor (AhR) in mice with DSS-induced colitis.
Topics & Concepts
Bifidobacterium bifidumColitisBifidobacteriumTumor necrosis factor alphaLipopolysaccharideChemistryInflammatory bowel diseaseOccludinBarrier functionMicrobiologyDextranIn vivoPharmacologyImmunologyBiologyLactobacillusBiochemistryTight junctionInternal medicineMedicineCell biologyDiseaseFermentationBiotechnologyGut microbiota and healthProbiotics and Fermented FoodsBarrier Structure and Function Studies