Adiponectin agonist ADP355 ameliorates doxorubicin-induced cardiotoxicity by decreasing cardiomyocyte apoptosis and oxidative stress
Dan Zhao, Chao Xue, Jiaqi Li, Ke Feng, Peng Zeng, Yuanli Chen, Yajun Duan, Shuang Zhang, Xiaoju Li, Jihong Han, Xiaoxiao Yang
Topics & Concepts
CardiotoxicityOxidative stressDoxorubicinSirtuinPharmacologyLactate dehydrogenaseApoptosisSuperoxide dismutaseReactive oxygen speciesAdiponectinSOD2Viability assayEndocrinologyChemistryMedicineInternal medicineBiochemistryToxicityChemotherapyEnzymeInsulin resistanceNAD+ kinaseInsulinChemotherapy-induced cardiotoxicity and mitigationCancer Treatment and PharmacologyCarbon Nanotubes in Composites