The Spo7 sequence LLI is required for Nem1-Spo7/Pah1 phosphatase cascade function in yeast lipid metabolism
Mona Mirheydari, Prabuddha Dey, Geordan J. Stukey, Yeonhee Park, Gil‐Soo Han, George Carman
Abstract
triacylglycerol/phospholipid synthesis, lipid droplet formation, nuclear/endoplasmic reticulum membrane morphology, vacuole fusion, and growth on glycerol medium). These findings advance the understanding of Nem1-Spo7 complex formation and its role in the phosphatase cascade that regulates the function of Pah1 phosphatidate phosphatase.
Topics & Concepts
BiochemistryEndoplasmic reticulumPhosphatidateBiologySaccharomyces cerevisiaePhosphataseAspergillus nidulansProtein phosphatase 2MutantYeastPhospholipidEnzymeGeneMembranePhosphatidic acidFungal and yeast genetics researchLipid metabolism and biosynthesisEndoplasmic Reticulum Stress and Disease