Moving closer towards a comprehensive view of tumor biology and microarchitecture using spatial transcriptomics
Young Min Park, De‐Chen Lin
Abstract
Spatial transcriptomic profiling of cancer has enabled spatial delineation of malignant transcriptional heterogeneity, intercellular communication, and organization of microanatomical structures within the tumor microenvironment. This technical breakthrough paves the way for the development of precision diagnostic methods and targeted therapies.
Topics & Concepts
TranscriptomeComputational biologyProfiling (computer programming)Tumor microenvironmentBiologyComputer scienceCancerGeneticsGene expressionGeneOperating systemSingle-cell and spatial transcriptomicsCancer Genomics and DiagnosticsCancer Cells and Metastasis