The role of iron metabolism in chronic diseases related to obesity
Fangyi Qiu, Lei Wu, Guang Yang, Cong Zhang, Xiaofang Liu, Xiance Sun, Xin Chen, Ningning Wang
Abstract
Obesity is one of the major public health problems threatening the world, as well as a potential risk factor for chronic metabolic diseases. There is growing evidence that iron metabolism is altered in obese people, however, the highly refined regulation of iron metabolism in obesity and obesity-related complications is still being investigated. Iron accumulation can affect the body's sensitivity to insulin, Type 2 diabetes, liver disease and cardiovascular disease. This review summarized the changes and potential mechanisms of iron metabolism in several chronic diseases related to obesity, providing new clues for future research.
Topics & Concepts
ObesityDiseaseDiabetes mellitusMedicineMetabolic diseaseMetabolismType 2 diabetesBioinformaticsChronic diseaseEndocrinologyBiologyPhysiologyInternal medicineIron Metabolism and DisordersHemoglobinopathies and Related DisordersErythropoietin and Anemia Treatment