Elevated levels of alcohol dehydrogenase aggravate ethanol-evoked cardiac remodeling and contractile anomalies through FKBP5-yap-mediated regulation of ferroptosis and ER stress
Lu Qi, Xing Qin, Chu Chen, Wei Yu, Jie Lin, Xiaoyu Liu, Rui Guo, Rüssel J. Reiter, Milad Ashrafizadeh, Ming Yuan, Jun Ren
Topics & Concepts
EthanolAlcohol dehydrogenaseAlcoholEndocrinologyInternal medicineMedicineCell biologyChemistryBiologyBiochemistryEndoplasmic Reticulum Stress and DiseaseCardiovascular Function and Risk FactorsHeme Oxygenase-1 and Carbon Monoxide