Litcius/Paper detail

Design and synthesis of 3-(4-pyridyl)-5-(4-sulfamido-phenyl)-1,2,4-oxadiazole derivatives as novel GSK-3β inhibitors and evaluation of their potential as multifunctional anti-Alzheimer agents

Min Wang, Tongtong Liu, Shiming Chen, Mingfei Wu, Jianfei Han, Zeng Li

2020European Journal of Medicinal Chemistry59 citationsDOIOpen Access PDF

Topics & Concepts

ChemistryGSK-3OxadiazoleNeuroprotectionGlycogen synthaseChemical synthesisPotencyKinasePharmacologyEnzymeBiochemistryStereochemistryCombinatorial chemistryIn vitroOrganic chemistryMedicineCholinesterase and Neurodegenerative DiseasesComputational Drug Discovery MethodsNuclear Receptors and Signaling