Injectable recombinant block polymer gel for sustained delivery of therapeutic protein in post traumatic osteoarthritis
Priya Katyal, Aubryanna Hettinghouse, Michael Meleties, Sadaf Hasan, Changhong Chen, Min Cui, Guodong Sun, Rajiv Menon, Bonnie Lin, Ravinder Regatte, Jin Kim Montclare, Chuan-ju Liu
Topics & Concepts
OsteoarthritisBiocompatibilityChondrocyteCartilageRecombinant DNAIn vivoCartilage oligomeric matrix proteinPharmacologyBiomedical engineeringMaterials scienceElastinAnterior cruciate ligamentAnabolismMedicineTransdermalMatrix (chemical analysis)CatabolismGenetically engineeredBiocompatible materialCancer researchTherapeutic effectScaffoldExtracellular matrixChemistryOsteoarthritis Treatment and MechanismsConnective tissue disorders researchHydrogels: synthesis, properties, applications