Chemotherapy-induced neutropenia and emerging agents for prevention and treatment: A review
Douglas W. Blayney, Lee Schwartzberg
Abstract
Highlights•Chemotherapy-induced neutropenia can lead to poor clinical outcomes.•CIN can lead to infections, hospitalizations, mortality, and lower chemotherapy dose intensity.•G-CSF agents have been the standard of care for the prevention of CIN for 30 years.•Emerging therapies will likely change the standard approach for CIN prevention.
Topics & Concepts
MedicineNeutropeniaChemotherapyIntensive care medicineStandard of careInternal medicineOncologyNeutropenia and Cancer InfectionsChemotherapy-related skin toxicityBlood disorders and treatments