Gefitinib induces EGFR and α5β1 integrin co-endocytosis in glioblastoma cells
Anne-Florence Blandin, Elisabete Cruz Da Silva, Marie-Cécile Mercier, Oleksandr Glushonkov, Pascal Didier, Stéphane Dedieu, Christophe Schneider, Jessica Devy, Nelly Étienne-Selloum, Monique Dontenwill, Laurence Choulier, Maxime Lehmann
Topics & Concepts
GefitinibEndocytosisEndosomeCancer researchIntegrinERBB3Cell biologyEGFR inhibitorsBiologyTyrosine kinaseEpidermal growth factor receptorCellSignal transductionReceptor tyrosine kinaseIntracellularReceptorBiochemistryGlioma Diagnosis and TreatmentCell Adhesion Molecules ResearchCellular transport and secretion