Litcius/Paper detail

Extrachromosomal DNA is associated with oncogene amplification and poor outcome across multiple cancers

Hoon Kim, Nam Nguyen, Kristen M. Turner, Sihan Wu, Amit D. Gujar, Jens Luebeck, Jihe Liu, Viraj Deshpande, Utkrisht Rajkumar, Sandeep Namburi, Samirkumar B. Amin, Eunhee Yi, Francesca Menghi, Johannes H. Schulte, Anton G. Henssen, Howard Y. Chang, Christine R. Beck, Paul S. Mischel, Vineet Bafna, Roel G.W. Verhaak

2020Nature Genetics635 citationsDOIOpen Access PDF

Topics & Concepts

BiologyExtrachromosomal DNAGeneticsOncogeneDNACancer researchCancerComputational biologyCell cyclePlasmidCancer Genomics and DiagnosticsGenetic factors in colorectal cancerMolecular Biology Techniques and Applications