Extrachromosomal DNA is associated with oncogene amplification and poor outcome across multiple cancers
Hoon Kim, Nam Nguyen, Kristen M. Turner, Sihan Wu, Amit D. Gujar, Jens Luebeck, Jihe Liu, Viraj Deshpande, Utkrisht Rajkumar, Sandeep Namburi, Samirkumar B. Amin, Eunhee Yi, Francesca Menghi, Johannes H. Schulte, Anton G. Henssen, Howard Y. Chang, Christine R. Beck, Paul S. Mischel, Vineet Bafna, Roel G.W. Verhaak
Topics & Concepts
BiologyExtrachromosomal DNAGeneticsOncogeneDNACancer researchCancerComputational biologyCell cyclePlasmidCancer Genomics and DiagnosticsGenetic factors in colorectal cancerMolecular Biology Techniques and Applications