Treg Cells Expressing the Coinhibitory Molecule TIGIT Selectively Inhibit Proinflammatory Th1 and Th17 Cell Responses
Nicole Joller, Ester Lozano, Patrick R. Burkett, Bonny Patel, Sheng Xiao, Chen Zhu, Junrong Xia, Tze Guan Tan, Esen Sefik, Vijay Yajnik, Arlene H. Sharpe, Francisco J. Quintana, Diane Mathis, Christophe Benoıst, David A. Hafler, Vijay K. Kuchroo
Topics & Concepts
TIGITFOXP3BiologyProinflammatory cytokineEffectorCell biologyT cellImmunologyRegulatory T cellCellImmune systemInflammationIL-2 receptorGeneticsT-cell and B-cell ImmunologyImmune Cell Function and InteractionImmunotherapy and Immune Responses