Heat and pressure-resistant room temperature irreversible sealing of hybrid PDMS–thermoplastic microfluidic devices <i>via</i> carbon–nitrogen covalent bonding and its application in a continuous-flow polymerase chain reaction
R. Sivakumar, Kieu The Loan Trinh, Nae Yoon Lee
Abstract
In this study, we have introduced a facile room-temperature strategy for irreversibly sealing polydimethylsiloxane to various thermoplastics using (3-aminopropyl)triethoxysilane (APTES) and [2-(3,4-epoxycyclohexyl)ethyl]trimethoxysilane (ECTMS).
Topics & Concepts
Materials sciencePolydimethylsiloxaneContact angleTriethoxysilaneSilaneX-ray photoelectron spectroscopySurface modificationEpoxyChemical engineeringMicrochannelCovalent bondComposite materialPolymerPolymer chemistryNanotechnologyChemistryOrganic chemistryEngineeringAdvanced Sensor and Energy Harvesting MaterialsMicrofluidic and Capillary Electrophoresis ApplicationsNanofabrication and Lithography Techniques