Litcius/Paper detail

Brief guide to assays for measuring health parameters using Caenorhabditis elegans

Syh-Yuan Hwang, Jongsun Lee, Seung‐Jae Lee

2025Molecules and Cells12 citationsDOIOpen Access PDF

Abstract

Assessing health parameters is essential for understanding the decline of physiological functions during aging. The nematode Caenorhabditis elegans serves as a powerful model in aging research. This paper introduces representative methods for evaluating health parameters using C. elegans and provides quantitative indicators of functional declines during aging. This manuscript will be useful for researchers unfamiliar with healthspan studies using C. elegans and may help perform physiological experiments for healthy aging.

Topics & Concepts

Caenorhabditis elegansComputational biologyBiologyGeneticsGeneGenetics, Aging, and Longevity in Model OrganismsSpaceflight effects on biology