Association between cardiorespiratory fitness and cerebrovascular reactivity to a breath-hold stimulus in older adults: influence of aerobic exercise training
Lyndsey E. DuBose, Timothy B. Weng, Gary L. Pierce, Conner Wharff, Lauren Reist, Chase Hamilton, Abby O’Deen, Kaitlyn Dubishar, Abbi D. Lane‐Cordova, Michelle W. Voss
Abstract
Earlier studies evaluating associations between cardiorespiratory fitness (CRF) and cerebrovascular reactivity (CVR) have demonstrated conflicting findings dependent on imaging modality or subject characteristics in individuals across a narrow range of CRF. This study demonstrates that CRF is nonlinearly associated with CVR measured by blood oxygen level dependent (BOLD) fMRI in a large sample of middle-aged and older adults across a wide range of CRF, suggesting that conflicting prior findings are related to the range of CRFs studied.
Topics & Concepts
Cardiorespiratory fitnessAerobic exerciseVO2 maxMedicinePhysical medicine and rehabilitationPhysical fitnessPsychologyPhysical therapyStimulus (psychology)CRFSCardiologyInternal medicineBlood pressureHeart rateCognitive psychologyComputer scienceNatural language processingConditional random fieldHeart Rate Variability and Autonomic ControlFunctional Brain Connectivity StudiesCardiovascular and exercise physiology