Exosome and <scp>epithelial–mesenchymal</scp> transition: A complex secret of cancer progression
Rajib Dhar, Arikketh Devi, Sukhamoy Gorai, Saurabh Kumar Jha, Αθανάσιος Αλεξίου, Marios Papadakis
Abstract
This short communication will enlighten the readers about the exosome and the epithelial-mesenchymal transition (EMT) related to several complicated events. It also highlighted the therapeutic potential of exosomes against EMT. Exosome toxicology, exosome heterogeneity, and a single exosome profiling approach are also covered in this article. In the future, exosomes could help us get closer to cancer vaccine and precision oncology.
Topics & Concepts
ExosomeMicrovesiclesEpithelial–mesenchymal transitionCancer researchmicroRNAComputational biologyBioinformaticsMedicineBiologyMetastasisCancerInternal medicineGeneGeneticsExtracellular vesicles in diseaseCancer-related molecular mechanisms researchMicroRNA in disease regulation