Selection of Payloads for Antibody–Drug Conjugates Targeting Ubiquitously Expressed Tumor-Associated Antigens: a Case Study
Bing Yao, Xiao Gao, Mo Dan, Can Yuan, Xixin Hu, Zhaopeng Sun, Xiwu Hui, Boning Liu, Pingkai Ouyang, Guoguang Chen
Topics & Concepts
AntigenDrugCytotoxic T cellAntibodyToxicityAntibody-drug conjugateMedicineIn vitroCancer researchPharmacologyMonoclonal antibodyChemistryInternal medicineImmunologyBiochemistryMonoclonal and Polyclonal Antibodies ResearchHER2/EGFR in Cancer ResearchCAR-T cell therapy research