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Tumor necrosis factor-α-induced protein 8-like 2 alleviates morphine antinociceptive tolerance through reduction of ROS-mediated apoptosis and MAPK/NF-κB signaling pathways

Zhong Yang, Feifei Zhang, Mannan Abdul, Jinhong Jiang, Yanqiang Li, Yeqi Li, Yin Cui, Yanhong Xing, Su Liu, Lu Chen

2023Neuropharmacology11 citationsDOI

Topics & Concepts

NociceptionMorphineDownregulation and upregulationDrug tolerancePharmacologyHyperalgesiaApoptosisMAPK/ERK pathwayMedicineSignal transductionTumor necrosis factor alphaReactive oxygen speciesNF-κBInflammationChemistryCell biologyEndocrinologyInternal medicineBiologyReceptorBiochemistryGenePain Mechanisms and TreatmentsIon channel regulation and functionNerve injury and regeneration
Tumor necrosis factor-α-induced protein 8-like 2 alleviates morphine antinociceptive tolerance through reduction of ROS-mediated apoptosis and MAPK/NF-κB signaling pathways | Litcius