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Taxifolin Protects Against 5-Fluorouracil-Induced Cardiotoxicity in Mice Through Mitigating Oxidative Stress, Inflammation, and Apoptosis: Possible Involvement of Sirt1/Nrf2/HO-1 Signaling

Mohammad H. Abukhalil, Zina M. Al‐Alami, Manal A. Alfwuaires, Muhammad Imran, Saleem H. Aladaileh, Osama Y. Althunibat

2025Cardiovascular Toxicology17 citationsDOI

Topics & Concepts

Oxidative stressCardiotoxicityInflammationApoptosisTaxifolinChemistryMedicinePharmacologyCancer researchImmunologyChemotherapyInternal medicineAntioxidantBiochemistryFlavonoidSirtuins and Resveratrol in MedicineChemotherapy-induced cardiotoxicity and mitigationGenomics, phytochemicals, and oxidative stress
Taxifolin Protects Against 5-Fluorouracil-Induced Cardiotoxicity in Mice Through Mitigating Oxidative Stress, Inflammation, and Apoptosis: Possible Involvement of Sirt1/Nrf2/HO-1 Signaling | Litcius