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Engineered mischarged transfer RNAs for correcting pathogenic missense mutations

Yichen Hou, Wen Zhang, Philip T. McGilvray, Marek Sobczyk, Tianxin Wang, Shao Huan Samuel Weng, Allen Huff, Sihao Huang, Noah Peña, Christopher D. Katanski, Tao Pan

2023Molecular Therapy26 citationsDOIOpen Access PDF

Topics & Concepts

Missense mutationTransfer RNANonsense mutationBiologyGeneticsMutantGenePoint mutationMutationRNATranslation (biology)Computational biologyMessenger RNARNA and protein synthesis mechanismsRNA modifications and cancerRNA Interference and Gene Delivery
Engineered mischarged transfer RNAs for correcting pathogenic missense mutations | Litcius