Metallaphotoredox aryl and alkyl radiomethylation for PET ligand discovery
Robert W. Pipal, Kenneth T. Stout, Patricia Z. Musacchio, Sumei Ren, Thomas J. A. Graham, Stefan Verhoog, Liza Gantert, Talakad G. Lohith, Alexander Schmitz, Hsiaoju Lee, David Hesk, Eric D. Hostetler, Ian W. Davies, David W. C. MacMillan
Topics & Concepts
RadiosynthesisChemistryArylIn vivoRadiochemistryPharmacophoreAlkylPositron emission tomographyCombinatorial chemistryPet imagingDrug discoveryTritiumLigand (biochemistry)Nuclear medicineStereochemistryOrganic chemistryBiochemistryMedicineBiologyReceptorPhysicsBiotechnologyNuclear physicsChemical Reactions and IsotopesEpigenetics and DNA MethylationAmino Acid Enzymes and Metabolism