A potential novel treatment strategy for breast cancer: The regulation of apoptosis and metastasis by mitochondria-targeted lupeol-triphenylphosphine derivatives
Xinyang Liu, Jing Yang, Xu Song, Haotian Zhang, Zengxin Wang, Jing Ma, Lina Guo, Xiaohui Du, Hongxia Cui
Topics & Concepts
ChemistryApoptosisCancer researchMetastasisIn vivoLupeolViability assayIn vitroReactive oxygen speciesCell growthCellCytotoxicityActivator (genetics)Cancer cellBreast cancerCell cultureMitochondrionHuman breastmicroRNATumor cellsCancerPharmacologyCell biologyCell migrationNatural product bioactivities and synthesisBiochemical Acid Research StudiesATP Synthase and ATPases Research