One-pot three-component synthesis of novel pyrazolo-acridine derivatives and assessment of their acetylcholinesterase inhibitory properties: An in vitro and in silico study
Muna Elmusa, Safa Elmusa, Samet Mert, Rahmi Kasımoğulları, Fikret Türkan, Mehmet Nuri Atalar, Ercan Bursal
Topics & Concepts
ChemistryAcridineIn silicoAcridine derivativesAcetylcholinesteraseIn vitroInhibitory postsynaptic potentialComponent (thermodynamics)Combinatorial chemistryStereochemistryBiochemistryOrganic chemistryEnzymeNeurosciencePhysicsBiologyThermodynamicsGeneSynthesis and biological activityCholinesterase and Neurodegenerative DiseasesMulticomponent Synthesis of Heterocycles