Pathophysiology of Dysphagia in Eosinophilic Esophagitis: Causes, Consequences, and Management
Edward J. Young, Hamish Philpott
Abstract
Eosinophilic esophagitis (EoE) is a leading cause of food bolus impaction in children and adults. The mechanism of dysphagia in EoE, particularly non-obstructive dysphagia, remains incompletely understood. While fibrostenotic processes appear to be critical in the development of dysphagia, somatosensory dysfunction and dysmotility also contribute. This review considers potential mechanisms of dysphagia and evaluates the utility of current and future treatment strategies in this context.
Topics & Concepts
DysphagiaEosinophilic esophagitisMedicineContext (archaeology)HepatologyIntensive care medicineGastroenterologyInternal medicinePathophysiologyEsophageal diseaseEsophagitisEsophagusSurgeryDiseasePaleontologyRefluxBiologyEosinophilic EsophagitisEosinophilic Disorders and Syndromes