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Injectable thermosensitive hydrogel based on hyaluronic acid and poloxamer for sustained bupivacaine release and prolonged analgesia

Junhui Yang, Qien Zhao, Jiahong Lu, Yingying Lv, Wenting Jiang, Xiaowei Chen, Shengyu Zhang, Wei Zhao, Lei Jiang, Jiantao Zhang

2025International Journal of Biological Macromolecules13 citationsDOI

Topics & Concepts

PoloxamerHyaluronic acidBupivacaineSelf-healing hydrogelsChemistryPoloxamer 407AnesthesiaPharmacologyMedicinePolymerPolymer chemistryOrganic chemistryAnatomyCopolymerAnesthesia and Pain ManagementPain Management and Opioid UseSpine and Intervertebral Disc Pathology
Injectable thermosensitive hydrogel based on hyaluronic acid and poloxamer for sustained bupivacaine release and prolonged analgesia | Litcius