Niclosamide affects intracellular TDP-43 distribution in motor neurons, activates mitophagy, and attenuates morphological changes under stress
Yosuke Kato, Kazuichi Sakamoto
Topics & Concepts
NiclosamideStress granuleMitophagyAmyotrophic lateral sclerosisCell biologyUbiquitinMotor neuronTARDBPChemistrySpinal cordBiologyAutophagyOxidative stressNeuroscienceBiochemistrySOD1ApoptosisTranslation (biology)MedicineGenePathologySuperoxide dismutaseMessenger RNAEcologyDiseaseAmyotrophic Lateral Sclerosis ResearchNeurogenetic and Muscular Disorders ResearchSynthetic Organic Chemistry Methods