Single-cell profiling of brain pericyte heterogeneity following ischemic stroke unveils distinct pericyte subtype-targeted neural reprogramming potential and its underlying mechanisms
Allison Loan, Nidaa Awaja, Margarita Lui, Charvi Syal, Yiren Sun, Sailendra Nath Sarma, Ragav Chona, William B Johnston, Alex Córdova, Devansh Saraf, Anabella Nakhlé, Kaela O’Connor, Jacob Thomas, Joseph Leung, Matthew Seegobin, Ling He, Fredric E. Wondisford, David J. Picketts, Eve C. Tsai, Hing Man Chan, Jing Wang
Abstract
pericytes.
Topics & Concepts
PericyteReprogrammingProfiling (computer programming)NeuroscienceCellMedicineBiologyComputer scienceEndothelial stem cellOperating systemIn vitroBiochemistryGeneticsNeuroinflammation and Neurodegeneration MechanismsBarrier Structure and Function StudiesSingle-cell and spatial transcriptomics