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Aortic Valve Repair in Pediatric Patients: 30 Years Single Center Experience

Johanna Schlein, Alexandra Kaider, Harald Gabriel, Dominik Wiedemann, Stephan Hornykewycz, Paul Simon, Eva Base, Ina Michel‐Behnke, Günther Laufer, Daniel Zimpfer

2022The Annals of Thoracic Surgery19 citationsDOIOpen Access PDF

Abstract

BACKGROUND: Valve repair is the procedure of choice for congenital aortic valve disease. With increasing experience, the surgical armamentarium broadened from simple commissurotomy to more complex techniques. We report our 30-year experience with pediatric aortic valve repair. METHODS: A retrospective chart review of all patients aged less than 18 years who underwent aortic valve repair from May 1985 to April 2020 was conducted. Mortality was cross-checked with the national health insurance database (96% complete mortality follow-up in April 2020). Primary study endpoints were survival and incidence of reoperations. RESULTS: From May 1985 until April 2020, 126 patients underwent aortic valve repair at a median age of 1.8 years (interquartile range, 0.2-10). Early mortality was 5.6% (7 of 126). All early deaths occurred in neonates with critical aortic stenosis undergoing commissurotomy. No early deaths were observed after 2002. Kaplan-Meier estimated survival was 90.8% (95% CI, 84.0-94.8) at 10 years, 86.9% (95% CI, 78.7-92.2) at 20 years, and 83.5% (95% CI, 71.7-90.6) at 30 years. The cumulative incidence of aortic valve replacement was 37% (95% CI, 27.7-46.3) at 10 years, 62.2% (95% CI, 50.1-72.1) at 20 years, and 67.4% (51.2-79.2) at 30 years. Nine patients had undergone re-repair of the aortic valve. The majority of valve replacements were Ross procedures. CONCLUSIONS: Our results support a repair-first strategy for patients with congenital heart disease and underline that aortic valve reconstruction can be a successful long-term solution. Longevity did not differ between aortic valve commissurotomy and complex aortic valve reconstruction.

Topics & Concepts

MedicineSingle CenterAortic valveCenter (category theory)SurgeryCrystallographyChemistryCongenital Heart Disease StudiesAortic Disease and Treatment ApproachesCardiac Valve Diseases and Treatments
Aortic Valve Repair in Pediatric Patients: 30 Years Single Center Experience | Litcius