Tocilizumab preserves renal function in rheumatoid arthritis with AA amyloidosis and end-stage kidney disease: Two case reports
Makoto Fukuda, Naoki Sawa, Junichi Hoshino, Kenichi Ohashi, Motoaki Miyazono, Yoshifumi Ubara
Abstract
duodenal biopsy showed a marked decrease of AA amyloid deposits. Conclusion: These two cases suggest that tocilizumab may preserve renal function in the setting of end-stage kidney disease and shift the point of no return for RA patients with AA amyloidosis and renal dysfunction.
Topics & Concepts
MedicineRheumatoid arthritisTocilizumabAmyloidosisRenal functionStage (stratigraphy)End stage renal diseaseKidney diseaseEnd-stage kidney diseaseInternal medicineDiseasePaleontologyBiologyAmyloidosis: Diagnosis, Treatment, OutcomesSystemic Lupus Erythematosus ResearchHepatitis C virus research