Quantifying constraint in the human mitochondrial genome
Nicole J. Lake, Kaiyue Ma, Wei Liu, Stephanie L. Battle, Kristen M. Laricchia, Grace Tiao, Daniela Puiu, Kenneth K.H. Ng, Justin D. Cohen, Alison G. Compton, Shannon Cowie, John Christodoulou, David R. Thorburn, Hongyu Zhao, Dan E. Arking, Shamil Sunyaev, Monkol Lek
Topics & Concepts
Mitochondrial DNAGenomeConstraint (computer-aided design)Human genomeComputational biologyBiologyEvolutionary biologyGeneticsGeneMathematicsGeometryMitochondrial Function and PathologyRNA and protein synthesis mechanismsGenomics and Phylogenetic Studies