Manipulation of Redox Metabolism Using Pharmacologic Ascorbate Opens a Therapeutic Window for Radio-Sensitization by ATM Inhibitors in Colorectal Cancer
Cameron M. Callaghan, Ibrahim M. Abukhiran, Amr H. Masaadeh, Richard Van Rheeden, Amanda L. Kalen, Samuel N. Rodman, Michael S. Petronek, Kranti A. Mapuskar, Benjamin N. George, Mitchell C. Coleman, Prabhat C. Goswami, Bryan G. Allen, Douglas R. Spitz, Joseph M. Caster
Topics & Concepts
Cancer researchClonogenic assayDNA damageColorectal cancerChemistryOxidative stressCancerPathologyMedicinePharmacologyCellInternal medicineBiochemistryDNAEffects of Radiation ExposureRadiation Therapy and DosimetryVitamin C and Antioxidants Research