Transformation of phytosterols into pregnatetraenedione by a combined microbial and chemical process
Yongjun Liu, Weiting Ji, Song Lu, Xinyi Tao, Ming Zhao, Bei Gao, Hao Meng, Feng-Qing Wang, Dongzhi Wei
Abstract
A 9-0HPDC-M hyperproducing strain with high selectivity and yield was constructed and a more efficient route to produce corticosteroids from the phytosterols via pregnatetraenedione was proposed.
Topics & Concepts
Transformation (genetics)Process (computing)ChemistryChemical transformationOrganic chemistryBiochemical engineeringFood scienceBiochemistryComputer scienceEngineeringOperating systemGeneSteroid Chemistry and BiochemistryPharmacogenetics and Drug MetabolismHormonal Regulation and Hypertension