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Understanding the impact of mannitol on physical stability and aerosolization of spray-dried protein powders for inhalation

Kinnari Santosh Arte, Cole W. Tower, Tarun Tejasvi Mutukuri, Yuan Chen, Sajal M. Patel, Eric J. Munson, Qi Zhou

2023International Journal of Pharmaceutics26 citationsDOIOpen Access PDF

Topics & Concepts

ExcipientSpray dryingMannitolCrystallinityAerosolizationChemistryParticle sizeChromatographyChemical engineeringOrganic chemistryInhalationCrystallographyMedicineEngineeringAnatomyPhysical chemistryInhalation and Respiratory Drug DeliveryMicroencapsulation and Drying ProcessesProtein purification and stability
Understanding the impact of mannitol on physical stability and aerosolization of spray-dried protein powders for inhalation | Litcius