MiR-497-3p induces Premature ovarian failure by targeting KLF4 to inactivate Klotho/PI3K/AKT/mTOR signaling pathway
Yuhan Zhou, Feifei Yuan, Chunlian Jia, Fen Chen, Fei Li, Lingyu Wang
Topics & Concepts
PI3K/AKT/mTOR pathwayGene knockdownKLF4Protein kinase BBiologyKlothoTUNEL assayCancer researchChromatin immunoprecipitationApoptosisCell biologySignal transductionMolecular biologyTranscription factorEndocrinologyGene expressionPromoterKidneyBiochemistrySOX2GeneKruppel-like factors researchReproductive Biology and FertilityParathyroid Disorders and Treatments