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Machine learning algorithms to predict risk of postoperative pneumonia in elderly with hip fracture

Jiale Guo, Qionghan He, Caiju Peng, Ru Dai, Wei Li, Zhichao Su, Yehai Li

2023Journal of Orthopaedic Surgery and Research17 citationsDOIOpen Access PDF

Abstract

BACKGROUND: Hip fracture (HF) is one of the most common fractures in the elderly and is significantly associated with high mortality and unfavorable prognosis. Postoperative pneumonia (POP), the most common postoperative complication of HF, can seriously affect patient prognosis and increase the burden on the healthcare system. The aim of this study was to develop machine learning models for identifying elderly patients at high risk of pneumonia after hip fracture surgery. METHODS: From May 2016 to November 2022, patients admitted to a single central hospital for HF served as the study population. We extracted data that could be collected within 24 h of patient admission. The dataset was divided into training and validation sets according to 70:30. Based on the screened risk factors, prediction models were developed using seven machine learning algorithms, namely CART, GBM, KNN, LR, NNet, RF, and XGBoost, and their performance was evaluated. RESULTS: which are used as features to build machine learning models. By evaluating the model's AUC value, accuracy, sensitivity, specificity, Kappa value, MCC value, Brier score value, calibration curve, and DCA curve, the model constructed by XGBoost algorithm has the best and near-perfect performance. CONCLUSION: The machine learning model we created is ideal for detecting elderly patients at high risk of POP after HF at an early stage.

Topics & Concepts

MedicineBrier scoreAlgorithmHip fractureMachine learningPneumoniaReceiver operating characteristicPopulationArtificial intelligenceInternal medicineSurgeryEmergency medicineOsteoporosisComputer scienceEnvironmental healthHip and Femur FracturesArtificial Intelligence in Healthcare and EducationMachine Learning in Healthcare