<i>Solanum anguivi</i>Lam. fruit preparations counteract the negative effects of a high-sugar diet on the glucose metabolism in<i>Drosophila melanogaster</i>
Aisha Musaazi Sebunya Nakitto, Silvia Rudloff, Christian Borsch, Anika E. Wagner
Abstract
homolog of PPARγ-co-activator 1α, a central player in mitochondrial biogenesis. Overall, the present study shows that SALF significantly lowered the HSD-induced glucose levels and increased the survival while the biomarkers of the energy metabolism were not affected.
Topics & Concepts
EndocrinologyInternal medicineCarbohydrate metabolismMitochondrial biogenesisBiologyMetabolismInsulinDiabetes mellitusMitochondrionBiochemistryMedicineInsect Utilization and EffectsNeurobiology and Insect Physiology ResearchAntioxidant Activity and Oxidative Stress