Key advances and application prospects of PROTAC technologies in the next 5 years
Shuanglin Qin, Xiaohe Xiao
Abstract
Proteolysis Targeting Chimeras (PROTACs) were considered as revolutionary solutions in the discovery and development of drugs during the past two decades. Since the inception of relevant research i...
Topics & Concepts
Key (lock)Drug discoveryComputer scienceComputational biologyData scienceMedicineBiologyBioinformaticsComputer securityProtein Degradation and InhibitorsPeptidase Inhibition and AnalysisUbiquitin and proteasome pathways