An organic transistor matrix for multipoint intracellular action potential recording
Yasutoshi Jimbo, Daisuke Sasaki, Takashi Ohya, Sunghoon Lee, Wonryung Lee, Faezeh Arab Hassani, Tomoyuki Yokota, Katsuhisa Matsuura, Shinjiro Umezu, Tatsuya Shimizu, Takao Someya
Abstract
Significance We successfully performed the intracellular action potential recording using organic electrochemical transistors (OECTs). A simultaneous multipoint recording with a 4 × 4 matrix of 5- × 5-μm 2 OECTs demonstrated the feasibility of potential high-resolution recording. The intracellular access was obtained by applying a pulse voltage to the drain electrode, and the amplitude of recorded signal reached 93 µA at maximum. This simple intracellular access method offers a higher signal-to-noise ratio and the waveform of membrane potential compared to the conventional extracellular field potential recording by OECT arrays.