Development of highly selective and sensitive molecularly imprinted polymer-based electrochemical sensors for tolvaptan assay in tablets and serum
Leyla Karadurmuş, Fatma Budak, Ahmet Çetinkaya, Esen Bellur Atıcı, Síbel A. Özkan
Abstract
M (TP)) were also obtained for TOL determination. The applicability of the proposed sensor was evaluated using tablet and commercial human serum samples. Interference and imprinting factor studies verified the selectivity and specificity of the proposed sensors, and the efficiency of the sensors was verified using an unprinted polymer for comparison at each step.
Topics & Concepts
Molecularly imprinted polymerElectrochemistryChromatographyCombinatorial chemistryChemistryNanotechnologyMaterials scienceOrganic chemistrySelectivityElectrodePhysical chemistryCatalysisAnalytical Chemistry and SensorsIon channel regulation and functionMicrofluidic and Capillary Electrophoresis Applications