Metal-free polychloromethyl radical-initiated cyclization of unactivated <i>N</i>-allylindoles towards pyrrolo[1,2-<i>a</i>]indoles
Yujia Shan, Zixian Yang, Jin‐Tao Yu, Changduo Pan
Abstract
A polychloromethylation-initiated cyclization of N -allyl-indoles towards pyrrolo[1,2- a ]indoles was developed using CH 2 Cl 2 and CHCl 3 as the di- and trichloromethyl radical sources.
Topics & Concepts
ChemistryRadical cyclizationSubstrate (aquarium)Medicinal chemistryFunctional groupMetalRadicalRadical initiatorScope (computer science)Reaction conditionsCombinatorial chemistryOrganic chemistryCatalysisPolymerComputer scienceOceanographyProgramming languagePolymerizationGeologyRadical Photochemical ReactionsCatalytic C–H Functionalization MethodsOxidative Organic Chemistry Reactions