Zinc Oxide Nanoparticle-Loaded Electrospun Polyvinylidene Fluoride Nanofibers as a Potential Face Protector against Respiratory Viral Infections
Hassan Nageh, Merna H. Emam, Fedaa Ali, Nasra F. Abdel Fattah, Mohamed Taha, Rehab Amin, Elbadawy A. Kamoun, Samah A. Loutfy, Amal Kasry
Abstract
values were obtained at concentrations of 0, 2, and 5% of ZnO-loaded PVDF; however, no cytotoxic effect was detected for the nanofibers. In 5% ZnO-loaded PVDF nanofibers, both the viral entry and its replication were inhibited in both the adsorption and virucidal antiviral mechanisms, making it a potent antiviral filter/mask. Therefore, ZnO-loaded PVDF nanofiber is a potentially prototyped filter embedded in a commercial face mask for use as an antiviral mask with a pronounced potential to reduce the spreading of infectious respiratory diseases, for example, COVID-19 and its analogues.
Topics & Concepts
NanofiberPolyvinylidene fluorideElectrospinningMaterials scienceFourier transform infrared spectroscopyNuclear chemistryChemical engineeringNanotechnologyChemistryComposite materialPolymerEngineeringInfection Control and VentilationVirus-based gene therapy research