Vorinostat is genotoxic and epigenotoxic in the mouse bone marrow cells at the human equivalent doses
Sabry M. Attia, Mohamed K. Al-Khalifa, Mohammed A. Al‐Hamamah, Moureq R. Alotaibi, Mohamed S. Attia, Sheikh F. Ahmad, Mushtaq Ahmad Ansari, Ahmed Nadeem, Saleh A. Bakheet
Topics & Concepts
VorinostatEpigeneticsBiologyDNA damageHistone deacetylase inhibitorMolecular biologyCarcinogenesisDNA methylationComet assayHistoneCancer researchHistone deacetylaseDNAGeneticsGene expressionGeneHistone Deacetylase Inhibitors ResearchT-cell and Retrovirus StudiesPhytochemical compounds biological activities