PFKFB3 inhibitors as potential anticancer agents: Mechanisms of action, current developments, and structure-activity relationships
Yinhu Wang, Chen Qu, Tingting Liu, Chunhui Wang
Topics & Concepts
Allosteric regulationChemistryGlycolysisPhosphofructokinase 2Activator (genetics)EnzymeCancer cellBiochemistryWarburg effectPhosphofructokinaseFructose 2,6-bisphosphateKinaseCancerBiologyReceptorGeneticsCancer, Hypoxia, and MetabolismATP Synthase and ATPases ResearchMitochondrial Function and Pathology