<i>ent</i>-Atisane diterpenoids: isolation, structure and bioactivity
Grace J. Drummond, Phillip Grant, Margaret A. Brimble
Abstract
Covering: up to 2020 ent-Atisane diterpenoids are a class of over 150 members with diverse structures and valuable bioactivities. These compounds share a curious history in which the synthesis of the archetypal member preceded its isolation from natural sources. In this review, we provide a comprehensive summary of the isolation, structure, and bioactivity of ent-atisane diterpenoids from their discovery in 1965 to the present day.
Topics & Concepts
Isolation (microbiology)ChemistryStereochemistryTerpeneComputational biologyBiologyMicrobiologyBioactive Natural Diterpenoids ResearchPlant-based Medicinal ResearchTraditional Chinese Medicine Analysis