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Specific modulation of the root immune system by a community of commensal bacteria

Paulo José Pereira Lima Teixeira, Nicholas R. Colaianni, Theresa F. Law, Jonathan M. Conway, Sarah Gilbert, Haofan Li, Isai Salas-González, Darshana Panda, Nicole M. Del Risco, Omri M. Finkel, Gabriel Castrillo, Piotr A. Mieczkowski, Corbin D. Jones, Jeffery L. Dangl

2021Proceedings of the National Academy of Sciences175 citationsDOIOpen Access PDF

Abstract

Significance In natural environments, plants establish intimate interactions with a wide diversity of microbes. It is unknown, however, how microbiota composed of commensal bacteria colonize roots in the face of a sophisticated plant immune system that evolved to recognize microbial-associated molecular patterns. We investigate the interaction between plant immune system function and the root microbiota. We report that root-associated commensal bacteria actively suppress the host immune response in the context of a community. Suppressors and nonsuppressors co-occur in the root microbiome and the presence of the former can enhance the colonization ability of the latter. We highlight the role of a specific sector of the plant immune system and its suppression in gating microbial access to the roots.

Topics & Concepts

Immune systemBiologyMicrobiomeContext (archaeology)BacteriaHost (biology)CommensalismColonizationMicrobiologyImmunologyEcologyGeneticsPaleontologyPlant Parasitism and ResistancePlant-Microbe Interactions and ImmunityLegume Nitrogen Fixing Symbiosis
Specific modulation of the root immune system by a community of commensal bacteria | Litcius