Litcius/Paper detail

Economic Impact of Allergic Diseases and Asthma—The <scp>HEAD</scp> Pan‐European Registry

Ioana Agache, Marı́a José Torres, Ibon Eguíluz‐Gracia, E. Bradatan, K El, Maria Beatrice Bilò, Federica Rivolta, Andrea Sangalli, Roxana Silvia Bumbăcea, Selda Ali, Darío Antolín‐Amérigo, Águeda Concepción Lario Cuenda, Vicente Javier Albendiz, Maria Miguel Oliveira, Paulo Nogueira, Loreto Carmona, HEAD Study Group

2025Allergy11 citationsDOIOpen Access PDF

Abstract

The Health Economics of Allergic Diseases (HEAD) registry is a European-based registry developed by the European Academy of Allergy and Clinical Immunology in collaboration with national allergy societies to facilitate standardised allergic disease management. Using an observational design, this first registry-based study describes care patterns for allergic diseases and their impact on the healthcare system (diagnostic and management costs), society (missed work/school days and disability pension/support) and patients (out-of-pocket costs) in 778 adults and children with allergic rhinitis, asthma, atopic dermatitis and food allergy, from four countries (Belgium, Italy, Romania and Spain). The average total costs per patient and per year were €1329.55 ± 1947.39, with indirect costs of €338.68 ± 1629.61. Direct costs consisted of €82.74 ± 585.90 for hospitalisations, €17.50 ± 125.07 for the emergency department, €172.94 ± 323.17 for specialists, €22.70 ± 132.42 for primary care, €4.85 ± 136.84 for psychologists, €21.24 ± 82.47 for diagnosis and €104.81 ± 469.26 for treatments. Indirect costs were out-of-pocket consultation fees (€16.24 ± 106.40), medications (€161.90 ± 710.58), transportation (€44.15 ± 218.51), private insurance (€16.77 ± 157.91), avoidance (€8.65 ± 92.99) and environmental control (€99.33 ± 955.23). Adults missed 1.02 ± 3.20 workdays, children missed 0.53 ± 2.18 schooldays and burdened their families with 1.38 ± 13.83 lost days. There was a high degree of heterogeneity across countries for management patterns and for costs. The significant burden of allergic diseases calls for immediate action for better management.

Topics & Concepts

AsthmaMedicineAllergic asthmaHead (geology)AllergyImmunologyPediatricsBiologyPaleontologyAsthma and respiratory diseasesOccupational exposure and asthmaAllergic Rhinitis and Sensitization