Expression of inducible factors reprograms CAR-T cells for enhanced function and safety
Anže Smole, Alexander Benton, Mathilde Poussin, Monika A. Eiva, Claudia Mezzanotte, Barbara Camisa, Béatrice Gréco, Prannda Sharma, Nicholas G. Minutolo, Falon Gray, Adham S. Bear, Miren L. Baroja, Casey Cummins, Chong Xu, Francesca Sanvito, Andrea Lang Goldgewicht, Tatiana Blanchard, Alba Rodríguez-García, Michael Klichinsky, Chiara Bonini, Carl H. June, Avery D. Posey, Gerald P. Linette, Beatriz M. Carreno, Monica Casucci, Daniel J. Powell
Topics & Concepts
Chimeric antigen receptorBiologyImmunotherapyTranscription factorImmune systemTransgeneCytokineComputational biologyCell biologyCancer immunotherapyImmunologyGeneGeneticsCAR-T cell therapy researchVirus-based gene therapy researchNanowire Synthesis and Applications