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Persistence of Bacteriophage Phi 6 on Porous and Nonporous Surfaces and the Potential for Its Use as an Ebola Virus or Coronavirus Surrogate

Carrie Whitworth, Yi Mu, Hollis Houston, Marla Martinez-Smith, Judith Noble‐Wang, Angela Coulliette-Salmond, Laura J. Rose

2020Applied and Environmental Microbiology75 citationsDOIOpen Access PDF

Abstract

Understanding the persistence of enveloped viruses helps inform infection control practices and procedures in health care facilities and community settings. These data convey to public health investigators that enveloped viruses can persist and remain infective on surfaces, thus demonstrating a potential risk for transmission. Under these laboratory-simulated Western indoor hospital conditions, we assessed the suitability of phi 6 as a surrogate for environmental persistence research related to enveloped viruses, including EBOV and coronaviruses.

Topics & Concepts

Ebola virusOutbreakCoronavirusVirologyPorous mediumPersistence (discontinuity)VirusPandemicCoronavirus disease 2019 (COVID-19)ChemistryMicrobiologyBiologyMedicinePorosityInfectious disease (medical specialty)DiseaseGeotechnical engineeringEngineeringOrganic chemistryPathologyInfection Control and VentilationViral Infections and Outbreaks ResearchDisaster Response and Management